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1TFZ

Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
4-hydroxyphenylpyruvate dioxygenasepolymer42446783.81UniProt (P93836)
Pfam (PF00903)
Arabidopsis thaliana (thale cress)4HPPD, HPD, HPPDase
2B
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
3C
(A)
(1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONEnon-polymer442.51Chemie (869)
4D
(A)
waterwater18.0202Chemie (HOH)
Sequence modifications
A: 2 - 424 (UniProt: P93836)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight46783.8
Non-Polymers*Number of molecules2
Total formula weight498.4
All*Total formula weight47282.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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