1TCX
HIV TRIPLE MUTANT PROTEASE COMPLEXED WITH INHIBITOR SB203386
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV PROTEASE | polymer | 99 | 10817.8 | 2 | UniProt (P04587) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (A) | (2R,4S,5S,1'S)-2-PHENYLMETHYL-4-HYDROXY-5-(TERT-BUTOXYCARBONYL)AMINO-6-PHENYL HEXANOYL-N-(1'-IMIDAZO-2-YL)-2'-METHYLPROPANAMIDE | non-polymer | 534.7 | 1 | Chemie (IM1) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P04587)
| PDB | External Database | Details |
|---|---|---|
| Ile 32 | Val 100 | engineered mutation |
| Val 47 | Ile 115 | engineered mutation |
| Ile 82 | Val 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21635.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 534.7 | |
| All* | Total formula weight | 22170.3 |
