1TBW

Ligand Induced Conformational Shift in the N-terminal Domain of GRP94, Open Conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Endoplasmin	polymer	236	26514.0	2	UniProt (P41148) Pfam (PF13589) In PDB	Canis lupus familiaris (dog)	94 kDa glucose-regulated protein, GRP94
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A, B	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	2	Chemie (AMP)
4	A, B	TETRAETHYLENE GLYCOL	non-polymer		194.2	5	Chemie (PG4)
5		water	water		18.0	231	Chemie (HOH)

Sequence modifications

A, B: 69 - 286 (UniProt: P41148)

PDB	External Database	Details
Gly 65	-	cloning artifact
Ser 66	-	cloning artifact
His 67	-	cloning artifact
Met 68	-	cloning artifact

A, B: 328 - 337 (UniProt: P41148)

PDB	External Database	Details
Gly 287	-	SEE REMARK 999
Gly 288	-	SEE REMARK 999
Gly 289	-	SEE REMARK 999
Gly 290	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53028.0
Non-Polymers*	Number of molecules	9
	Total formula weight	1714.2
All*	Total formula weight	54742.2

*Water molecules are not included.