1TA6
Crystal structure of thrombin in complex with compound 14b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | thrombin | polymer | 287 | 33080.0 | 1 | UniProt (P00734) Pfam (PF09396) Pfam (PF00089) In PDB | Homo sapiens (human) | Coagulation factor II |
| 2 | B | Hirudin | polymer | 11 | 1376.4 | 1 | UniProt (P28504) In PDB | Hirudo medicinalis | |
| 3 | A | 1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE | non-polymer | 479.0 | 1 | Chemie (177) | |||
| 4 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
B: 355 - 365 (UniProt: P28504)
| PDB | External Database | Details |
|---|---|---|
| Ala 362 | Glu 62 | CONFLICT |
| Ala 365 | Gln 65 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34456.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 479.0 | |
| All* | Total formula weight | 34935.4 |
