1T9A
Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetolactate synthase, mitochondrial | polymer | 677 | 73597.7 | 2 | UniProt (P07342) Pfam (PF02776) Pfam (PF00205) Pfam (PF02775) | Saccharomyces cerevisiae (baker's yeast) | Acetohydroxy-acid synthase, ALS, AHAS |
| 2 | C, I (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | D, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, L (A, B) | METHYL 2-[4-METHOXY-6-METHYL-1,3,5-TRAZIN-2-YL(METHYL)CARBAMOYLSULFAMOYL]BENZOATE | non-polymer | 395.4 | 2 | Chemie (1TB) | |||
| 5 | F (A) | 2-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}PROPANE-1-THIOL | non-polymer | 212.3 | 1 | Chemie (YF3) | |||
| 6 | G, N (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 7 | H, K (A, B) | PROPYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 220.1 | 2 | Chemie (P23) | |||
| 8 | M (B) | 5-{[ETHYL(METHYL)AMINO]METHYL}-2-METHYL-5,6-DIHYDROPYRIMIDIN-4-AMINE | non-polymer | 180.3 | 1 | Chemie (YF4) | |||
| 9 | O, P (A, B) | water | water | 18.0 | 913 | Chemie (HOH) |
Sequence modifications
A, B: 58 - 687 (UniProt: P07342)
| PDB | External Database | Details |
|---|---|---|
| Met 11 | - | cloning artifact |
| His 12 | - | cloning artifact |
| His 13 | - | cloning artifact |
| His 14 | - | cloning artifact |
| His 15 | - | cloning artifact |
| His 16 | - | cloning artifact |
| His 17 | - | cloning artifact |
| Ser 18 | - | cloning artifact |
| Ser 19 | - | cloning artifact |
| Gly 20 | - | cloning artifact |
| Leu 21 | - | cloning artifact |
| Val 22 | - | cloning artifact |
| Pro 23 | - | cloning artifact |
| Arg 24 | - | cloning artifact |
| Gly 25 | - | cloning artifact |
| Ser 26 | - | cloning artifact |
| Gly 27 | - | cloning artifact |
| Met 28 | - | cloning artifact |
| Lys 29 | - | cloning artifact |
| Glu 30 | - | cloning artifact |
| Thr 31 | - | cloning artifact |
| Ala 32 | - | cloning artifact |
| Ala 33 | - | cloning artifact |
| Ala 34 | - | cloning artifact |
| Lys 35 | - | cloning artifact |
| Phe 36 | - | cloning artifact |
| Glu 37 | - | cloning artifact |
| Arg 38 | - | cloning artifact |
| Gln 39 | - | cloning artifact |
| His 40 | - | cloning artifact |
| Met 41 | - | cloning artifact |
| Asp 42 | - | cloning artifact |
| Ser 43 | - | cloning artifact |
| Pro 44 | - | cloning artifact |
| Asp 45 | - | cloning artifact |
| Leu 46 | - | cloning artifact |
| Gly 47 | - | cloning artifact |
| Thr 48 | - | cloning artifact |
| Asp 49 | - | cloning artifact |
| Asp 50 | - | cloning artifact |
| Asp 51 | - | cloning artifact |
| Asp 52 | - | cloning artifact |
| Lys 53 | - | cloning artifact |
| Ala 54 | - | cloning artifact |
| Met 55 | - | cloning artifact |
| Gly 56 | - | cloning artifact |
| Ser 57 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147195.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3321.4 | |
| All* | Total formula weight | 150516.7 |
