1T7L

Crystal Structure of Cobalamin-Independent Methionine Synthase from T. maritima

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase	polymer	766	89410.3	2	UniProt (Q9X112) Pfam (PF08267) Pfam (PF01717)	Thermotoga maritima	Methionine synthase, vitamin-B12 independent isozyme, Cobalamin-independent methionine synthase
2	C, E (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	D, F (A, B)	MESO-ERYTHRITOL	non-polymer		122.1	2	Chemie (MRY)
4	G, H (A, B)	water	water		18.0	618	Chemie (HOH)

Sequence modifications

A, B: 2 - 734 (UniProt: Q9X112)

PDB	External Database	Details
Met -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
Gly -24	-	expression tag
Lys -23	-	expression tag
Pro -22	-	expression tag
Ile -21	-	expression tag
Pro -20	-	expression tag
Asn -19	-	expression tag
Pro -18	-	expression tag
Leu -17	-	expression tag
Leu -16	-	expression tag
Gly -15	-	expression tag
Leu -14	-	expression tag
Asp -13	-	expression tag
Ser -12	-	expression tag
Thr -11	-	expression tag
Glu -10	-	expression tag
Asn -9	-	expression tag
Leu -8	-	expression tag
Tyr -7	-	expression tag
Phe -6	-	expression tag
Gln -5	-	expression tag
Gln -4	-	expression tag
Ile -3	-	expression tag
Asp -2	-	expression tag
Pro -1	-	expression tag
Phe 0	-	expression tag
Thr 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	178820.5
Non-Polymers*	Number of molecules	4
	Total formula weight	436.4
All*	Total formula weight	179256.9

*Water molecules are not included.