1T5X
HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 181 | 21042.7 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B (B) | HLA class II histocompatibility antigen, DRB1-1 beta chain | polymer | 190 | 22080.7 | 1 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (human) | MHC class I antigen DRB1*1, DR-1, DR1 |
| 3 | C (C) | 15-mer peptide fragment of Regulatory protein MIG1 | polymer | 15 | 1603.8 | 1 | UniProt (P27705) | Regulatory protein CAT4 | |
| 4 | D (D) | Enterotoxin type C-3 | polymer | 239 | 27721.1 | 1 | UniProt (P0A0L5) Pfam (PF01123) Pfam (PF02876) | Staphylococcus aureus | SEC3; enterotoxin typeC3 |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
C: 7 - 14 (UniProt: P27705)
D: 1 - 239 (UniProt: P0A0L5)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | insertion |
| Ala 1 | - | insertion |
| Tyr 2 | - | insertion |
| Ser 3 | - | insertion |
| Asp 4 | - | insertion |
| Gln 5 | - | insertion |
| Ala 6 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Ser 43 | Lys 70 | engineered mutation |
| Phe 45 | Leu 72 | engineered mutation |
| Lys 46 | Ala 73 | engineered mutation |
| Trp 47 | His 74 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72448.3 | |
| All* | Total formula weight | 72448.3 |
