1T5X

HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HLA class II histocompatibility antigen, DR alpha chain	polymer	181	21042.7	1	UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB	Homo sapiens (human)	MHC class II antigen DRA
2	B	HLA class II histocompatibility antigen, DRB1-1 beta chain	polymer	190	22080.7	1	UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB	Homo sapiens (human)	MHC class I antigen DRB1*1, DR-1, DR1
3	C	15-mer peptide fragment of Regulatory protein MIG1	polymer	15	1603.8	1	UniProt (P27705) In PDB		Regulatory protein CAT4
4	D	Enterotoxin type C-3	polymer	239	27721.1	1	UniProt (P0A0L5) Pfam (PF01123) Pfam (PF02876) In PDB	Staphylococcus aureus	SEC3; enterotoxin typeC3
5		water	water		18.0	221	Chemie (HOH)

Sequence modifications

C: 7 - 14 (UniProt: P27705)

PDB	External Database	Details
Ala 0	-	insertion
Ala 1	-	insertion
Tyr 2	-	insertion
Ser 3	-	insertion
Asp 4	-	insertion
Gln 5	-	insertion
Ala 6	-	insertion

D: 1 - 239 (UniProt: P0A0L5)

PDB	External Database	Details
Ser 43	Lys 70	engineered mutation
Phe 45	Leu 72	engineered mutation
Lys 46	Ala 73	engineered mutation
Trp 47	His 74	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	72448.3
All*	Total formula weight	72448.3

*Water molecules are not included.