1T5C
Crystal structure of the motor domain of human kinetochore protein CENP-E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Centromeric protein E | polymer | 349 | 39335.4 | 2 | UniProt (Q02224) Pfam (PF00225) | Homo sapiens (human) | CENP-E protein |
| 2 | C, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 4 | E, H (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 5 | F (A) | PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID) | non-polymer | 302.4 | 1 | Chemie (PIN) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 342 (UniProt: Q02224)
| PDB | External Database | Details |
|---|---|---|
| Ala 300 | Pro 300 | SEE REMARK 999 |
| Leu 343 | - | cloning artifact |
| Glu 344 | - | cloning artifact |
| His 345 | - | cloning artifact |
| His 346 | - | cloning artifact |
| His 347 | - | cloning artifact |
| His 348 | - | cloning artifact |
| His 349 | - | cloning artifact |
| His 350 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78670.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1267.4 | |
| All* | Total formula weight | 79938.2 |
