1T49
Allosteric Inhibition of Protein Tyrosine Phosphatase 1B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein-tyrosine phosphatase, non-receptor type 1 | polymer | 298 | 34720.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase 1B, PTP-1B |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID (4-SULFAMOYL-PHENYL)-AMIDE | non-polymer | 658.3 | 1 | Chemie (892) | |||
| 4 | D (A) | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34720.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 682.6 | |
| All* | Total formula weight | 35403.2 |
