1T38

HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BOUND TO DNA CONTAINING O6-METHYLGUANINE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3'	polymer	13	4005.6	1
2	B (C)	5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'	polymer	13	3951.6	1
3	C (A)	Methylated-DNA--protein-cysteine methyltransferase	polymer	188	20339.4	1	UniProt (P16455) Pfam (PF02870) Pfam (PF01035)	Homo sapiens (human)	6-O-methylguanine-DNA methyltransferase
4	D (A)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

A: 1 - 176 (UniProt: P16455)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ser 145	Cys 145	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	28296.6
All*	Total formula weight	28296.6

*Water molecules are not included.