1T26

Plasmodium falciparum lactate dehydrogenase complexed with NADH and 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	L-lactate dehydrogenase	polymer	322	34977.6	1	UniProt (Q27743) Pfam (PF00056) Pfam (PF02866) In PDB	Plasmodium falciparum (malaria parasite P. falciparum)	LDH-P
2	A	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	1	Chemie (NAI)
3	A	4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID	non-polymer		146.1	1	Chemie (GBD)
4		water	water		18.0	270	Chemie (HOH)

Sequence modifications

A: 17 - 329 (UniProt: Q27743)

PDB	External Database	Details
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34977.6
Non-Polymers*	Number of molecules	2
	Total formula weight	811.6
All*	Total formula weight	35789.2

*Water molecules are not included.