1T24

Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	L-lactate dehydrogenase	polymer	322	34977.6	1	UniProt (Q27743) Pfam (PF00056) Pfam (PF02866) In PDB	Plasmodium falciparum (malaria parasite P. falciparum)	LDH-P
2	A	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
3	A	4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID	non-polymer		130.1	1	Chemie (OXQ)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	322	Chemie (HOH)

Sequence modifications

A: 17 - 329 (UniProt: Q27743)

PDB	External Database	Details
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34977.6
Non-Polymers*	Number of molecules	3
	Total formula weight	885.6
All*	Total formula weight	35863.2

*Water molecules are not included.