1T03
HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer (complex P)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | Synthetic oligonucleotide template | polymer | 27 | 8367.4 | 1 | |||
| 2 | B (P) | Synthetic oligonucleotide primer | polymer | 21 | 6430.3 | 1 | |||
| 3 | C (A) | POL polyprotein | polymer | 558 | 64249.7 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | |
| 4 | D (B) | POL polyprotein | polymer | 437 | 51095.6 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | |
| 5 | E (L) | monoclonal antibody light chain | polymer | 211 | 23362.7 | 1 | Pfam (PF07654) UniProt (by SIFTS) (P01837) | Mus musculus (house mouse) | |
| 6 | F (H) | monoclonal antibody heavy chain | polymer | 225 | 24000.8 | 1 | Mus musculus (house mouse) | ||
| 7 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 1 - 558 (UniProt: P03366)
B: 1 - 429 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Cys 258 | Gln 425 | engineered mutation |
| Ser 280 | Cys 447 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 280 | Cys 447 | engineered mutation |
| Gly 430 | - | cloning artifact |
| Gly 431 | - | cloning artifact |
| His 432 | - | expression tag |
| His 433 | - | expression tag |
| His 434 | - | expression tag |
| His 435 | - | expression tag |
| His 436 | - | expression tag |
| His 437 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 177506.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 177530.7 |
