1SZR
A Dimer interface mutant of ornithine decarboxylase reveals structure of gem diamine intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, D, A, B) | Ornithine decarboxylase | polymer | 425 | 47004.4 | 4 | UniProt (P07805) | Trypanosoma brucei brucei | ODC |
| 2 | E, F (C, D) | PYRIDOXINE-5'-PHOSPHATE | non-polymer | 249.2 | 2 | Chemie (PXP) PubChem (1055) | |||
| 3 | G (A) | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | non-polymer | 306.2 | 1 | Chemie (PLG) PubChem (445062) | |||
| 4 | H (B) | N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE | non-polymer | 363.3 | 1 | Chemie (ORX) PubChem (20335329) PubChem (22811264) PubChem (447380) | |||
| 5 | I, J, K, L (C, D, A, B) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
C, D, A, B: 3 - 425 (UniProt: P07805)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| Ala 294 | Lys 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 188017.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1167.8 | |
| All* | Total formula weight | 189185.3 |
