1SZN
THE STRUCTURE OF ALPHA-GALACTOSIDASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | alpha-galactosidase | polymer | 417 | 45610.9 | 1 | GenBank (1580816) Pfam (PF16499) Pfam (PF17801) UniProt (by SIFTS) (Q92456) In PDB | Hypocrea jecorina | |
| 2 | B, E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G11052OE) | |||
| 4 | D | beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G32484KU) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 623 | Chemie (HOH) |
Sequence modifications
A: 1 - 417 (GenBank: 1580816)
| PDB | External Database | Details |
|---|---|---|
| Leu 37 | Val 64 | SEE REMARK 999 |
| Pro 70 | Val 97 | SEE REMARK 999 |
| Ala 72 | Thr 99 | SEE REMARK 999 |
| Ala 88 | Asp 115 | SEE REMARK 999 |
| Asn 148 | Ala 175 | SEE REMARK 999 |
| Phe 151 | Ala 178 | SEE REMARK 999 |
| Lys 153 | Gln 180 | SEE REMARK 999 |
| Thr 161 | Ser 188 | SEE REMARK 999 |
| Asp 165 | Glu 192 | SEE REMARK 999 |
| Thr 167 | Asn 194 | SEE REMARK 999 |
| Gly 185 | Asn 212 | SEE REMARK 999 |
| His 196 | Arg 223 | SEE REMARK 999 |
| Met 202 | Leu 229 | SEE REMARK 999 |
| Gln 207 | Val 234 | SEE REMARK 999 |
| Ser 216 | Glu 243 | SEE REMARK 999 |
| Asp 225 | Gly 252 | SEE REMARK 999 |
| Asn 230 | Glu 257 | SEE REMARK 999 |
| Arg 236 | His 263 | SEE REMARK 999 |
| Leu 238 | Ile 265 | SEE REMARK 999 |
| Leu 240 | Met 267 | SEE REMARK 999 |
| Leu 245 | Met 272 | SEE REMARK 999 |
| Asp 249 | Gly 276 | SEE REMARK 999 |
| Met 258 | Ile 285 | SEE REMARK 999 |
| Asn 297 | Glu 324 | SEE REMARK 999 |
| Asn 300 | Glu 327 | SEE REMARK 999 |
| Ile 327 | Val 354 | SEE REMARK 999 |
| Val 335 | Tyr 362 | SEE REMARK 999 |
| Tyr 337 | Asn 364 | SEE REMARK 999 |
| Phe 341 | Tyr 368 | SEE REMARK 999 |
| Val 355 | Met 382 | SEE REMARK 999 |
| Ile 360 | His 387 | SEE REMARK 999 |
| Ala 362 | Val 389 | SEE REMARK 999 |
| Thr 363 | Arg 390 | SEE REMARK 999 |
| Asn 369 | Ser 396 | SEE REMARK 999 |
| His 378 | Arg 405 | SEE REMARK 999 |
| Ser 386 | Thr 413 | SEE REMARK 999 |
| Asp 389 | Ser 416 | SEE REMARK 999 |
| Ala 398 | Thr 425 | SEE REMARK 999 |
| Gln 415 | Arg 442 | SEE REMARK 999 |
| Arg 416 | Asn 443 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45610.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3156.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 48951.9 |
