1SR5
ANTITHROMBIN-ANHYDROTHROMBIN-HEPARIN TERNARY COMPLEX STRUCTURE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Antithrombin-III | polymer | 432 | 49101.0 | 1 | UniProt (P01008) Pfam (PF00079) | Homo sapiens (human) | ATIII, PRO0309 |
| 2 | B (B) | Prothrombin | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | Coagulation factor II |
| 3 | C (C) | Prothrombin | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II |
| 4 | D (D) | 4-deoxy-2,3,6-tri-O-methyl-alpha-D-xylo-hexopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfo-alpha-D-glucopyranose-(1-4)-(2R,3R,4S,5S,6S)-6-(dihydroxymethyl)-3,4-dimethoxytetrahydro-2H-pyran-2,5-diol-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-(2R,3R,4S,5S,6R)-6-(dihydroxymethyl)-3,4-dimethoxytetrahydro-2H-pyran-2,5-diol-(1-4)-1,5-anhydro-3-O-methyl-2,6-di-O-sulfo-D-glucitol | branched | 1815.7 | 1 | BIRD (PRD_900079) | heparin heptasaccharide | ||
| 5 | E, F, G (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | H (C) | 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose | non-polymer | 500.4 | 1 | Chemie (GU4) | |||
| 7 | I, J, K (A, B, C) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 82977.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1815.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1164.0 | |
| All* | Total formula weight | 85957.5 |
