1SLH

Mycobacterium tuberculosis dUTPase complexed with magnesium and dUDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Deoxyuridine 5'-triphosphate nucleotidohydrolase	polymer	174	17992.3	3	UniProt (P0A552) Pfam (PF00692) UniProt (by SIFTS) (P9WNS5) In PDB	Mycobacterium tuberculosis	dUTPase, dUTP pyrophosphatase
2	A, B, C	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
3	A, B, C	DEOXYURIDINE-5'-DIPHOSPHATE	non-polymer		388.2	3	Chemie (DUD)
4	A	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
5		water	water		18.0	40	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 154 (UniProt: P0A552)

PDB	External Database	Details
Met -19	-	cloning artifact
Gly -18	-	cloning artifact
Ser -17	-	cloning artifact
Ser -16	-	cloning artifact
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	cloning artifact
Ser -8	-	cloning artifact
Gly -7	-	cloning artifact
Leu -6	-	cloning artifact
Val -5	-	cloning artifact
Pro -4	-	cloning artifact
Arg -3	-	cloning artifact
Gly -2	-	cloning artifact
Ser -1	-	cloning artifact
His 0	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	53976.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1481.7
All*	Total formula weight	55458.6

*Water molecules are not included.