1SKX
Structural Disorder in the Complex of Human PXR and the Macrolide Antibiotic Rifampicin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Orphan nuclear receptor PXR | polymer | 313 | 36035.6 | 1 | UniProt (O75469) Pfam (PF00104) | Homo sapiens (human) | Pregnane X receptor, Orphan nuclear receptor PAR1, Steroid and xenobiotic receptor, SXR |
| 2 | B (A) | RIFAMPICIN | non-polymer | 822.9 | 1 | Chemie (RFP) | |||
| 3 | C (A) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 130 - 431 (UniProt: O75469)
| PDB | External Database | Details |
|---|---|---|
| Met 119 | - | initiating methionine |
| Lys 120 | - | expression tag |
| Lys 121 | - | expression tag |
| Gly 122 | - | expression tag |
| His 123 | - | expression tag |
| His 124 | - | expression tag |
| His 125 | - | expression tag |
| His 126 | - | expression tag |
| His 127 | - | expression tag |
| His 128 | - | expression tag |
| Gly 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36035.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 822.9 | |
| All* | Total formula weight | 36858.6 |
