1SIX

Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Deoxyuridine 5'-triphosphate nucleotidohydrolase	polymer	174	17992.3	1	UniProt (P0A552) Pfam (PF00692) UniProt (by SIFTS) (P9WNS5) In PDB	Mycobacterium tuberculosis	dUTPase, dUTP pyrophosphatase
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE	non-polymer		467.2	1	Chemie (DUP)
4	A	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
5		water	water		18.0	118	Chemie (HOH)

Sequence modifications

A: 1 - 154 (UniProt: P0A552)

PDB	External Database	Details
Met -19	-	cloning artifact
Gly -18	-	cloning artifact
Ser -17	-	cloning artifact
Ser -16	-	cloning artifact
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	cloning artifact
Ser -8	-	cloning artifact
Gly -7	-	cloning artifact
Leu -6	-	cloning artifact
Val -5	-	cloning artifact
Pro -4	-	cloning artifact
Arg -3	-	cloning artifact
Gly -2	-	cloning artifact
Ser -1	-	cloning artifact
His 0	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17992.3
Non-Polymers*	Number of molecules	3
	Total formula weight	613.6
All*	Total formula weight	18605.9

*Water molecules are not included.