1SI3
Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3' | polymer | 9 | 2808.7 | 1 | |||
| 2 | B (A) | Eukaryotic translation initiation factor 2C 1 | polymer | 149 | 17377.6 | 1 | UniProt (Q9UL18) Pfam (PF02170) | Homo sapiens (human) | eIF2C 1, eIF-2C 1, Putative RNA-binding protein Q99, Argonaute1 |
| 3 | C (A) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A: 225 - 369 (UniProt: Q9UL18)
| PDB | External Database | Details |
|---|---|---|
| Gly 221 | - | cloning artifact |
| Ser 222 | - | cloning artifact |
| His 223 | - | cloning artifact |
| Mse 224 | - | cloning artifact |
| Mse 232 | Met 232 | modified residue |
| Mse 273 | Met 273 | modified residue |
| Mse 362 | Met 362 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20186.3 | |
| All* | Total formula weight | 20186.3 |
