1SHL
CASPASE-7 IN COMPLEX WITH FICA ALLOSTERIC INHIBITOR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Caspase-7 | polymer | 245 | 28118.1 | 2 | UniProt (P55210) Pfam (PF00656) In PDB | Homo sapiens (human) | ICE-like apoptotic protease 3, ICE-LAP3, Apoptotic protease Mch-3, CMH-1 |
2 | A, B | 5-FLUORO-1H-INDOLE-2-CARBOXYLIC ACID-(2-MERCAPTO-ETHYL)-AMIDE | non-polymer | 238.3 | 2 | Chemie (FXN) |
Sequence modifications
A, B: 57 - 199 (UniProt: P55210)
A, B: 210 - 303 (UniProt: P55210)
PDB | External Database | Details |
---|---|---|
Ala 192 | Asp 192 | engineered mutation |
Gln 304 | - | expression tag |
Leu 305 | - | expression tag |
His 306 | - | expression tag |
His 307 | - | expression tag |
His 308 | - | expression tag |
His 309 | - | expression tag |
His 310 | - | expression tag |
His 311 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56236.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 476.6 | |
All* | Total formula weight | 56712.7 |