1SD3

Crystal structure of the GLUR6 ligand binding core in complex with 2S,4R-4-methylglutamate at 1.8 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glutamate receptor, ionotropic kainate 2	polymer	259	29371.6	2	UniProt (P42260) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	Glutamate receptor 6, IONOTROPIC KAINATE 2, GluR6
2	C, D (A, B)	2S,4R-4-METHYLGLUTAMATE	non-polymer		160.1	2	Chemie (SYM)
3	E, F (A, B)	water	water		18.0	424	Chemie (HOH)

Sequence modifications

A, B: 2 - 117 (UniProt: P42260)

PDB	External Database	Details
Gly 1	-	cloning artifact

A, B: 120 - 259 (UniProt: P42260)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58743.3
Non-Polymers*	Number of molecules	2
	Total formula weight	320.3
All*	Total formula weight	59063.6

*Water molecules are not included.