1SC4
Crystal structure of the human caspase-1 C285A mutant after removal of malonate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Interleukin-1 beta convertase | polymer | 178 | 19837.8 | 1 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (human) | IL-1BC, IL-1 beta converting enzyme, ICE, Interleukin-1 beta converting enzyme, P45, Caspase-1, CASP-1 |
| 2 | B | Interleukin-1 beta convertase | polymer | 88 | 10258.8 | 1 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (human) | IL-1BC, IL-1 beta converting enzyme, ICE, Interleukin-1 beta converting enzyme, P45, Caspase-1, CASP-1 |
| 3 | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A: 120 - 297 (UniProt: P29466)
| PDB | External Database | Details |
|---|---|---|
| Ala 285 | Cys 285 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30096.5 | |
| All* | Total formula weight | 30096.5 |
