1SB1
Novel Non-Covalent Thrombin Inhibitors Incorporating P1 4,5,6,7-Tetrahydrobenzothiazole Arginine Side Chain Mimetics
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Prothrombin | polymer | 29 | 3432.8 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | coagulation factor II |
| 2 | B (H) | Prothrombin | polymer | 258 | 29651.1 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | coagulation factor II |
| 3 | C (I) | hirugen | polymer | 9 | 1250.2 | 1 | UniProt (P28504) | ||
| 4 | D, E (H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | F (H) | N-(BENZYLSULFONYL)-3-CYCLOHEXYLALANYL-N-(2-AMINO-1,3-BENZOTHIAZOL-6-YL)PROLINAMIDE | non-polymer | 569.7 | 1 | Chemie (165) | |||
| 6 | G, H, I (L, H, I) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34334.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 615.7 | |
| All* | Total formula weight | 34949.9 |
