1S6Q
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R147681
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | POL polyprotein [Contains: Reverse transcriptase] | polymer | 560 | 64501.0 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus 1 | HIV-1 RT |
2 | B | POL polyprotein [Contains: Reverse transcriptase] | polymer | 430 | 50281.8 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | Human immunodeficiency virus 1 | HIV-1 RT |
3 | A | 4-[4-(2,4,6-TRIMETHYL-PHENYLAMINO)-PYRIMIDIN-2-YLAMINO]-BENZONITRILE | non-polymer | 329.4 | 1 | Chemie (TPB) |
Sequence modifications
A: 1 - 560 (UniProt: P03366)
B: 1 - 430 (UniProt: P03366)
PDB | External Database | Details |
---|---|---|
Ser 280 | Cys 447 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 280 | Cys 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 114782.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 329.4 | |
All* | Total formula weight | 115112.1 |