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1S5D

Cholera holotoxin with an A-subunit Y30S mutation, Crystal form 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cholera enterotoxin, A chainpolymer24027152.91UniProt (P01555)
Pfam (PF01375)
Vibrio choleraeNAD(+)--diphthamide ADP- ribosyltransferase, Cholera enterotoxin A subunit
2B, C, D, E, F
(D, E, F, G, H)
cholera toxin B protein (CTB)polymer10311623.35UniProt (P01556)
Pfam (PF01376)
Vibrio cholerae
3G
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
4H, J, L, N, P
(A, D, E, F, G)
GLYCEROLnon-polymer92.15Chemie (GOL)
5I, K, M, O, Q
(D, E, F, G, H)
beta-D-galactopyranosenon-polymer180.25Chemie (GAL)
6R, S, T, U, V...
(A, D, E, F, G...)
waterwater18.0603Chemie (HOH)
Sequence modifications
A: 1 - 240 (UniProt: P01555)
PDBExternal DatabaseDetails
Ser 30Tyr 30engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight85269.2
Non-Polymers*Number of molecules11
Total formula weight1384.2
All*Total formula weight86653.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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