1S4P
Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p: ternary complex with GDP/Mn and methyl-alpha-mannoside acceptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycolipid 2-alpha-mannosyltransferase | polymer | 348 | 41349.2 | 2 | UniProt (P27809) Pfam (PF01793) | Saccharomyces cerevisiae (baker's yeast) | Alpha-1,2-mannosyltransferase |
| 2 | C (C) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G80966KZ) | |||
| 3 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E, K (A, B) | methyl alpha-D-mannopyranoside | non-polymer | 194.2 | 2 | Chemie (MMA) | |||
| 5 | F, L (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 6 | G, H, M, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) PubChem (312) | |||
| 7 | I, O (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 8 | J, P (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) PubChem (23831) | |||
| 9 | Q, R (A, B) | water | water | 18.0 | 853 | Chemie (HOH) |
Sequence modifications
A, B: 97 - 442 (UniProt: P27809)
| PDB | External Database | Details |
|---|---|---|
| Glu 95 | - | cloning artifact |
| Phe 96 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82698.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1821.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2003.1 | |
| All* | Total formula weight | 86523.1 |
