1S3R

Crystal structure of the human-specific toxin intermedilysin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	intermedilysin	polymer	535	59064.9	2	UniProt (Q9LCB8) Pfam (PF01289) Pfam (PF17440)	Streptococcus intermedius
2	C, D, E, F (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	G, H (A, B)	water	water		18.0	451	Chemie (HOH)

Sequence modifications

A, B: 34 - 532 (UniProt: Q9LCB8)

PDB	External Database	Details
Met -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Gly 8	-	expression tag
Met 9	-	expression tag
Ala 10	-	expression tag
Ser 11	-	expression tag
Met 12	-	expression tag
Thr 13	-	expression tag
Gly 14	-	expression tag
Gly 15	-	expression tag
Gln 16	-	expression tag
Gln 17	-	expression tag
Met 18	-	expression tag
Gly 19	-	expression tag
Arg 20	-	expression tag
Asp 21	-	expression tag
Leu 22	-	expression tag
Tyr 23	-	expression tag
Asp 24	-	expression tag
Asp 25	-	expression tag
Asp 26	-	expression tag
Asp 27	-	expression tag
Lys 28	-	expression tag
Asp 29	-	expression tag
Arg 30	-	expression tag
Trp 31	-	expression tag
Gly 32	-	expression tag
Ser 33	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	118129.8
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	118514.0

*Water molecules are not included.