1S3I
Crystal structure of the N terminal hydrolase domain of 10-formyltetrahydrofolate dehydrogenase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 10-formyltetrahydrofolate dehydrogenase | polymer | 310 | 34081.8 | 1 | UniProt (P28037) Pfam (PF00551) Pfam (PF02911) | Rattus norvegicus (Norway rat) | 10-FTHFDH, FBP-CI |
| 2 | B, C, D, E, F (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 5 | Chemie (BME) | |||
| 3 | G (A) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 1 - 310 (UniProt: P28037)
| PDB | External Database | Details |
|---|---|---|
| Asp 42 | Leu 42 | SEE REMARK 999 |
| Val 51 | Arg 51 | SEE REMARK 999 |
| Pro 52 | Ala 52 | SEE REMARK 999 |
| Asp 283 | Glu 283 | SEE REMARK 999 |
| Asp 284 | His 284 | SEE REMARK 999 |
| Asp 310 | Ala 310 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34081.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 390.7 | |
| All* | Total formula weight | 34472.5 |
