1S14

Crystal structure of Escherichia coli Topoisomerase IV ParE 24kDa subunit

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Topoisomerase IV subunit B	polymer	194	21728.4	2	UniProt (P20083) Pfam (PF02518)	Escherichia coli
2	C, D (A, B)	NOVOBIOCIN	non-polymer		612.6	2	Chemie (NOV) PubChem (54686757) PubChem (54686783) PubChem (54686913) PubChem (54733713) PubChem (54734224) PubChem (58973932) PubChem (54678491) PubChem (54740845) PubChem (54713167) PubChem (54675769) PubChem (54693838) PubChem (57940280) PubChem (89848142) PubChem (71719647) PubChem (73896877) PubChem (88590404) PubChem (92209309) PubChem (92215931) PubChem (92535854) PubChem (118146199) PubChem (124086375) PubChem (124540942) PubChem (92402742) PubChem (118343815) PubChem (124364481) PubChem (167020105) PubChem (134693076) PubChem (149370231) PubChem (154435011) PubChem (166960227) PubChem (173862280)
3	E, F (A, B)	water	water		18.0	526	Chemie (HOH)

Sequence modifications

A, B: 1001 - 1217 (UniProt: P20083)

PDB	External Database	Details
-	Arg 93	deletion
-	Leu 94	deletion
-	His 95	deletion
-	Ala 96	deletion
-	Gly 97	deletion
-	Gly 98	deletion
-	Lys 99	deletion
-	Phe 100	deletion
-	Ser 101	deletion
-	Asn 102	deletion
-	Lys 103	deletion
-	Asn 104	deletion
-	Tyr 105	deletion
-	Gln 106	deletion
-	Phe 107	deletion
-	Ser 108	deletion
-	Gly 109	deletion
-	Gly 110	deletion
-	Leu 111	deletion
-	His 112	deletion
-	Gly 113	deletion
-	Val 114	deletion
-	Gly 115	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43456.8
Non-Polymers*	Number of molecules	2
	Total formula weight	1225.2
All*	Total formula weight	44682.0

*Water molecules are not included.