1S0X
Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nuclear receptor ROR-alpha | polymer | 270 | 31514.3 | 1 | UniProt (P35398) Pfam (PF00104) In PDB | Homo sapiens (human) | Nuclear receptor RZR-alpha |
2 | A | CHOLEST-5-EN-3-YL HYDROGEN SULFATE | non-polymer | 466.7 | 1 | Chemie (C3S) | |||
3 | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A: 271 - 523 (UniProt: P35398)
PDB | External Database | Details |
---|---|---|
Gly 254 | - | cloning artifact |
Ser 255 | - | cloning artifact |
Ser 256 | - | cloning artifact |
His 257 | - | expression tag |
His 258 | - | expression tag |
His 259 | - | expression tag |
His 260 | - | expression tag |
His 261 | - | expression tag |
His 262 | - | expression tag |
Leu 263 | - | expression tag |
Glu 264 | - | expression tag |
Val 265 | - | expression tag |
Leu 266 | - | expression tag |
Phe 267 | - | expression tag |
Gln 268 | - | expression tag |
Gly 269 | - | expression tag |
Pro 270 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31514.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 466.7 | |
All* | Total formula weight | 31981.0 |