1RWX
Crystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-yloxy)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-butyric acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-1 beta convertase | polymer | 178 | 19869.8 | 1 | UniProt (P29466) Pfam (PF00656) | Homo sapiens (human) | IL-1BC, IL-1 beta converting enzyme, ICE, Interleukin-1 beta converting enzyme, P45, Caspase-1, CASP-1 |
| 2 | B (B) | Interleukin-1 beta convertase | polymer | 88 | 10258.8 | 1 | UniProt (P29466) Pfam (PF00656) | Homo sapiens (human) | IL-1BC, IL-1 beta converting enzyme, ICE, Interleukin-1 beta converting enzyme, P45, Caspase-1, CASP-1 |
| 3 | C (A) | 4-OXO-3-{6-[4-(QUINOXALIN-2-YLOXY)-BENZOYLAMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-BUTYRIC ACID | non-polymer | 560.6 | 1 | Chemie (YBH) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30128.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 560.6 | |
| All* | Total formula weight | 30689.2 |
