1RW8
Crystal Structure of TGF-beta receptor I kinase with ATP site inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TGF-beta receptor type I | polymer | 301 | 34451.6 | 1 | UniProt (P36897) Pfam (PF00069) In PDB | Homo sapiens (human) | TGFR-1, TGF-beta type I receptor, Serine/threonine-protein kinase receptor R4, SKR4, Activin receptor-like kinase 5, ALK-5 |
| 2 | A | 3-(4-FLUOROPHENYL)-2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOLE | non-polymer | 293.3 | 1 | Chemie (580) | |||
| 3 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34451.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 293.3 | |
| All* | Total formula weight | 34744.9 |
