1RS8
Bovine endothelial NOS heme domain with D-lysine-D-nitroarginine amide bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric-oxide synthase, endothelial | polymer | 416 | 46854.0 | 2 | UniProt (P29473) Pfam (PF02898) | Bos taurus (cattle) | EC-NOS, NOS, type III, NOSIII, Endothelial NOS, eNOS, Constitutive NOS, cNOS |
| 2 | C, J (A, B) | CACODYLATE ION | non-polymer | 137.0 | 2 | Chemie (CAC) | |||
| 3 | D, K (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | F, L (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 6 | G, M (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 7 | H, N (A, B) | L-LYSYL-N~5~-[(Z)-(2,2-DIHYDROXYHYDRAZINO)(IMINO)METHYL]-L-ORNITHINAMIDE | non-polymer | 348.4 | 2 | Chemie (DP2) | |||
| 8 | I, O (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | P, Q (A, B) | water | water | 18.0 | 441 | Chemie (HOH) |
Sequence modifications
A, B: 67 - 482 (UniProt: P29473)
| PDB | External Database | Details |
|---|---|---|
| Arg 100 | Cys 99 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93708.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 3053.9 | |
| All* | Total formula weight | 96762.0 |
