1RQC

Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	formylmethionine deformylase	polymer	185	22048.0	10	UniProt (Q8I372) Pfam (PF01327)	Plasmodium falciparum (malaria parasite P. falciparum)
2	K, L, M, N, O... (A, B, C, D, E...)	COBALT (II) ION	non-polymer		58.9	10	Chemie (CO)
3	AA, BA, CA, DA, U... (G, H, I, J, A...)	water	water		18.0	149	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 63 - 239 (UniProt: Q8I372)

PDB	External Database	Details
Mse 96	Met 96	modified residue
Mse 100	Met 100	modified residue
Mse 212	Met 212	modified residue
Leu 240	-	expression tag
Glu 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	220480.5
Non-Polymers*	Number of molecules	10
	Total formula weight	589.3
All*	Total formula weight	221069.8

*Water molecules are not included.