1RO7
Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analogue, CMP-3FNeuAc.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | alpha-2,3/8-sialyltransferase | polymer | 259 | 30730.4 | 4 | UniProt (Q9LAK3) Pfam (PF06002) | Campylobacter jejuni | |
| 2 | E (B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 3 | F, G, H, I (C) | CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID | non-polymer | 632.4 | 4 | Chemie (CSF) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 259 (UniProt: Q9LAK3)
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | Met 1 | modified residue |
| Ser 53 | Ile 53 | engineered mutation |
| Mse 77 | Met 77 | modified residue |
| Mse 136 | Met 136 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 122921.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2647.9 | |
| All* | Total formula weight | 125569.5 |
