1RNJ
Crystal structure of inactive mutant dUTPase complexed with substrate analogue imido-dUTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Deoxyuridine 5'-triphosphate nucleotidohydrolase | polymer | 152 | 16301.6 | 1 | UniProt (P06968) Pfam (PF00692) In PDB | Escherichia coli | dUTPase, dUTP pyrophosphatase |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | A | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DUP) | |||
| 4 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 5 | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 2 - 152 (UniProt: P06968)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Asn 90 | Asp 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16301.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 735.7 | |
| All* | Total formula weight | 17037.4 |
