1RHK
Crystal structure of the complex of caspase-3 with a phenyl-propyl-ketone inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-3 | polymer | 147 | 16639.9 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | Cysteine protease CPP32, Yama protein, CPP-32, Apopain, CASP-3, SREBP cleavage activity 1, SCA-1 |
| 2 | B (B) | Caspase-3 | polymer | 102 | 11910.6 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | Cysteine protease CPP32, Yama protein, CPP-32, Apopain, CASP-3, SREBP cleavage activity 1, SCA-1 |
| 3 | C (C) | acetyl-asp-glu-val-fpr | polymer | 5 | 604.6 | 1 | BIRD (PRD_000231) | ||
| 4 | D, E (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
B: 310 - 402 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Glu 324 | Asp 190 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 29155.2 | |
| All* | Total formula weight | 29155.2 |
