1RHK
Crystal structure of the complex of caspase-3 with a phenyl-propyl-ketone inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Caspase-3 | polymer | 147 | 16639.9 | 1 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (human) | Cysteine protease CPP32, Yama protein, CPP-32, Apopain, CASP-3, SREBP cleavage activity 1, SCA-1 |
2 | B | Caspase-3 | polymer | 102 | 11910.6 | 1 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (human) | Cysteine protease CPP32, Yama protein, CPP-32, Apopain, CASP-3, SREBP cleavage activity 1, SCA-1 |
3 | C | acetyl-asp-glu-val-fpr | polymer | 5 | 604.6 | 1 | BIRD (PRD_000231) | ||
4 | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
B: 310 - 402 (UniProt: P42574)
PDB | External Database | Details |
---|---|---|
Glu 324 | Asp 190 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 29155.2 | |
All* | Total formula weight | 29155.2 |