1RB3
DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DIHYDROFOLATE REDUCTASE | polymer | 159 | 18020.3 | 2 | UniProt (P0ABQ4) Pfam (PF00186) In PDB | Escherichia coli | DHFR |
2 | A, B | METHOTREXATE | non-polymer | 454.4 | 2 | Chemie (MTX) | |||
3 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
4 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 159 (UniProt: P0ABQ4)
PDB | External Database | Details |
---|---|---|
Asp 37 | Asn 37 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36040.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2395.7 | |
All* | Total formula weight | 38436.3 |