1RAK
Bacterial cytosine deaminase D314S mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytosine deaminase | polymer | 430 | 47832.0 | 1 | UniProt (P25524) Pfam (PF07969) | Escherichia coli | Cytosine aminohydrolase |
| 2 | B (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 3 | C (A) | (4S)-5-FLUORO-4-HYDROXY-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE | non-polymer | 132.1 | 1 | Chemie (FPY) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence modifications
A: -1 - 426 (UniProt: P25524)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| Met 0 | - | cloning artifact |
| Ala 1 | Ser 1 | engineered mutation |
| Ser 314 | Asp 314 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47832.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 280.0 | |
| All* | Total formula weight | 48112.0 |
