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1RA2

DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROFOLATE REDUCTASEpolymer15918020.31UniProt (P0ABQ4)
Pfam (PF00186)
Escherichia coliDHFR
2B
(A)
FOLIC ACIDnon-polymer441.41Chemie (FOL)
3C
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
4D
(A)
waterwater18.0138Chemie (HOH)
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
PDBExternal DatabaseDetails
Asp 37Asn 37conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18020.3
Non-Polymers*Number of molecules2
Total formula weight1184.8
All*Total formula weight19205.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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