1R6D
Crystal Structure of DesIV double mutant (dTDP-glucose 4,6-dehydratase) from Streptomyces venezuelae with NAD and DAU bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TDP-glucose-4,6-dehydratase | polymer | 337 | 36497.9 | 1 | UniProt (Q9ZGH3) Pfam (PF16363) | Streptomyces venezuelae | dTDP-glucose 4,6-dehydratase |
| 2 | B (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 3 | C (A) | 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE | non-polymer | 564.3 | 1 | Chemie (DAU) | |||
| 4 | D (A) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
A: 1 - 337 (UniProt: Q9ZGH3)
| PDB | External Database | Details |
|---|---|---|
| Asn 128 | Asp 128 | engineered mutation |
| Gln 129 | Glu 129 | engineered mutation |
| Lys 287 | Glu 287 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36497.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1227.8 | |
| All* | Total formula weight | 37725.7 |
