1R5V
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, C) | H-2 class II histocompatibility antigen, E-K alpha chain | polymer | 180 | 20962.4 | 2 | UniProt (P04224) Pfam (PF00993) Pfam (PF07654) | Mus musculus (house mouse) | |
| 2 | B, E (E, F) | artificial peptide | polymer | 13 | 1410.7 | 2 | |||
| 3 | C, F (B, D) | MHC H2-IE-beta | polymer | 185 | 21737.2 | 2 | UniProt (P18468) Pfam (PF00969) Pfam (PF07654) | Mus musculus (house mouse) | |
| 4 | G, H, I, J, K... (A, E, B, C, F...) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
B, D: 32 - 215 (UniProt: P18468)
| PDB | External Database | Details |
|---|---|---|
| Ala 31 | - | cloning artifact |
| Ser 38 | Cys 11 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 88220.5 | |
| All* | Total formula weight | 88220.5 |
