1R55
Crystal structure of the catalytic domain of human ADAM 33
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ADAM 33 | polymer | 214 | 23567.6 | 1 | UniProt (Q9BZ11) Pfam (PF01421) In PDB | Homo sapiens (human) | A disintegrin and metalloproteinase domain 33 |
2 | B | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G21381MC) | |||
3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | A | (2S,3R)-N~4~-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-N~1~,2-dihydroxy-3-(2-methylpropyl)butanediamide | non-polymer | 331.4 | 1 | Chemie (097) | |||
7 | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A: 204 - 409 (UniProt: Q9BZ11)
PDB | External Database | Details |
---|---|---|
Gln 231 | Asn 231 | engineered mutation |
Ser 410 | - | cloning artifact |
Gly 411 | - | cloning artifact |
His 412 | - | expression tag |
His 413 | - | expression tag |
His 414 | - | expression tag |
His 415 | - | expression tag |
His 416 | - | expression tag |
His 417 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23567.6 | |
Branched | Number of molecules | 1 |
Total formula weight | 910.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 507.8 | |
All* | Total formula weight | 24986.2 |