1R54
Crystal structure of the catalytic domain of human ADAM33
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADAM 33 | polymer | 214 | 23567.6 | 1 | UniProt (Q9BZ11) Pfam (PF01421) | Homo sapiens (human) | A disintegrin and metalloproteinase domain 33 |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | G (A) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 204 - 409 (UniProt: Q9BZ11)
| PDB | External Database | Details |
|---|---|---|
| Gln 231 | Asn 231 | engineered mutation |
| Ser 410 | - | cloning artifact |
| Gly 411 | - | cloning artifact |
| His 412 | - | expression tag |
| His 413 | - | expression tag |
| His 414 | - | expression tag |
| His 415 | - | expression tag |
| His 416 | - | expression tag |
| His 417 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23567.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 176.4 | |
| All* | Total formula weight | 24168.4 |
