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1R1S

Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
GRB2-related adaptor protein 2polymer10011823.34UniProt (O89100)
Pfam (PF00017)
Mus musculus (house mouse)GADS protein, Growth factor receptor binding protein, GRBLG, GRB-2-like protein, GRB2L, Hematopoietic cell-associated adaptor protein GrpL, GRB-2-related monocytic adapter protein, Monocytic adapter, MONA, Adapter protein GRID
2B, D, F, H
(B, D, F, H)
LAT pY226 peptidepolymer7855.84
3I, J, K, L, M...
(A, C, E, G)
SULFATE IONnon-polymer96.17Chemie (SO4)
4P, Q, R, S, T...
(A, B, C, D, E...)
waterwater18.0441Chemie (HOH)
Sequence modifications
A, C, E, G: 52 - 149 (UniProt: O89100)
PDBExternal DatabaseDetails
Gly 50-cloning artifact
Ser 51-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight50716.3
Non-Polymers*Number of molecules7
Total formula weight672.4
All*Total formula weight51388.8
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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