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1QYW

Crystal structure of human estrogenic 17beta-hydroxysteroid dehydrogenase complex with androstanedione and NADP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Estradiol 17 beta-dehydrogenase 1polymer32734887.81UniProt (P14061)
Pfam (PF00106)
Homo sapiens (human)17-beta-HSD 1, Placental 17-beta-hydroxysteroid dehydrogenase, 20 alpha- hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH
2B
(A)
5ALPHA-ANDROSTAN-3,17-DIONEnon-polymer288.41Chemie (5SD)
3C
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E
(A)
waterwater18.0218Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34887.8
Non-Polymers*Number of molecules3
Total formula weight1123.9
All*Total formula weight36011.8
*Water molecules are not included.

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PDB entries from 2025-12-10

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