1QX3

Conformational restrictions in the active site of unliganded human caspase-3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Apopain	polymer	257	29589.6	1	UniProt (P42574) Pfam (PF00656) In PDB	Homo sapiens (human)	Cysteine protease CPP32, Yama protein, CPP-32, Caspase-3, CASP-3, SREBP cleavage activity 1, SCA-1
2		water	water		18.0	147	Chemie (HOH)

Sequence modifications

A: 29 - 277 (UniProt: P42574)

PDB	External Database	Details
Leu 278	-	expression tag
Glu 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29589.6
All*	Total formula weight	29589.6

*Water molecules are not included.