1QX2

X-ray Structure of Calcium-loaded Calbindomodulin (A Calbindin D9k Re-engineered to Undergo a Conformational Opening) at 1.44 A Resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Vitamin D-dependent calcium-binding protein, intestinal	polymer	76	8518.8	2	UniProt (P02633) Pfam (PF01023) Pfam (PF00036) In PDB	Bos taurus (cattle)	CABP, Calbindin D9K
2	A, B	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
3	B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4		water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B: 1 - 75 (UniProt: P02633)

PDB	External Database	Details
Fme 0	-	initiating methionine
Ile 6	Leu 9	engineered mutation
Ala 9	Ile 12	engineered mutation
Val 12	Lys 15	engineered mutation
Phe 13	Tyr 16	engineered mutation
Ile 23	Leu 26	engineered mutation
Val 31	Leu 34	engineered mutation
Met 32	Leu 35	engineered mutation
Leu 35	Glu 38	engineered mutation
Gly 36	Phe 39	engineered mutation
Met 43	Pro 46	engineered mutation
Met 49	Leu 52	engineered mutation
Ile 50	Phe 53	engineered mutation
Val 53	Leu 56	engineered mutation
Leu 67	Gln 70	engineered mutation
Met 69	Leu 72	engineered mutation
Met 70	Val 73	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	17037.5
Non-Polymers*	Number of molecules	6
	Total formula weight	291.1
All*	Total formula weight	17328.7

*Water molecules are not included.