1QWU
Golgi alpha-mannosidase II D341N mutant complex with 5-F-guloside
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Alpha-mannosidase II | polymer | 1045 | 119700.6 | 1 | UniProt (Q24451) Pfam (PF01074) Pfam (PF09261) Pfam (PF21260) Pfam (PF07748) Pfam (PF18230) In PDB | Drosophila melanogaster (fruit fly) | Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II |
| 2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | (2R,3S,4R,5S)-2,6-difluoro-2-(hydroxymethyl)oxane-3,4,5-triol | non-polymer | 200.1 | 1 | Chemie (GUL) | |||
| 5 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | water | water | 18.0 | 1025 | Chemie (HOH) |
Sequence modifications
A: 13 - 1045 (UniProt: Q24451)
| PDB | External Database | Details |
|---|---|---|
| Arg 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| Ser 3 | - | cloning artifact |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| Gly 10 | - | cloning artifact |
| Glu 11 | - | cloning artifact |
| Phe 12 | - | cloning artifact |
| Asn 341 | Asp 404 | engineered mutation |
| Lys 907 | Glu 970 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 119700.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 604.9 | |
| All* | Total formula weight | 120305.6 |
